Immunoglobulin G3, Human Plasma

Catalogue Number: 16-16-090707-3-ART

Manufacturer:Athens Research
Preservative:Liquid in 20 mM phosphate, pH 7.4, with 150 mM NaCl and 0.05% NaN3.
Molecular Weight:170,000 Da
Ph:ph 7.4
Physical state:Liquid
Type:Immunoglobulins
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 1 mg

Description

Description: Like IgG1, IgG3 activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.