Kininogen, High Molecular Weight, Human Plasma

Catalogue Number: 16-16-110914-H-ART

Manufacturer:Athens Research
Preservative:Frozen in 10 mM Na acetate, pH 5.5, with 250 mM NaCl
Molecular Weight:120000
Ph:pH 5.5
Physical state:Frozen
Type:Protease Inhibitor Protein
Shipping Condition:Dry Ice
Unit(s): 100 ug

Description

Description: High Molecular Weight kininogen, synthesized by hepatocytes, is a multifunctional protein. It is the precursor protein of bradykinin. In addition it is a cofactor in the activation of factor XI, XII, and prekallikrein and a major extra-cellular cysteine proteinase inhibitor. Kininogens inhibit systemic proteases which are thought to have a part in various diseases such as cancer, muscular dystrophy and joint disease.