LRP4 (Extracellular) (KIAA0816, LDLR)
Catalogue Number: 167596-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS pH7.4, 50% glycerol. |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | S207-27 |
| Isotype: | IgG2a |
| Immunogen: | Fusion protein corresponding to aa26- 350 from the extracellular N-terminus domain of mouse LTP4 |
| Application: | ICC, IF, WB |
Description
Description: Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.
Additional Text
Caution
FOR RESEARCH USE ONLY
Accession Number
NP_112612.2
Specificity
Recognizes LRP4 (Extracellular). Species Crossreactivity: Mouse, Rat. Detects ~215kD. Degradation product can be seen at ~150kD
Purification
Protein G purified
Uniprot ID
Q8V156
Antibody Clonality
Monoclonal
167596 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations