Actin, Smooth Muscle (ACTA2, Actin Alpha 2 Smooth Muscle Aorta, Actin Aortic Smooth Muscle, Actin Vascular Smooth Muscle, ACTSA, ACTVS, Alpha 2 Actin, Alpha Actin 2, Alpha Cardiac Actin, Alpha Smooth Muscle, Alpha-actin-2, Aortic Smooth Muscle, ASMA, Cell
Catalogue Number: 168642-AF-HRP-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in 10mM PBS. Labeled with horseradish peroxidase (HRP). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | actin, aortic smooth muscle|ACTSA|alpha-cardiac actin|cell growth-inhibiting gene 46 protein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 1A4 |
| Isotype: | IgG2a, kappa |
| Immunogen: | N-Terminal decapeptide of alpha smooth muscle isoform of actin, conjugated to KLH. Cellular Localization: Cytoplasmic |
| Application: | ELISA, FC, IF, IHC |
Description
Description: Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Additional Text
Gene Name
ACTA2
Gene ID
59
Purification
Protein A/G Purified
Specificity
Recognizes human Actin. Species Crossreactivity: babboon, monkey, bovine, porcine, sheep, goat, feline, canine, rabbit, mouse, rat, guinea pig and chicken.
Uniprot ID
P62736
Antibody Clonality
Monoclonal
Full Name
Actin, Smooth Muscle (ACTA2, Actin Alpha 2 Smooth Muscle Aorta, Actin Aortic Smooth Muscle, Actin Vascular Smooth Muscle, ACTSA, ACTVS, Alpha 2 Actin, Alpha Actin 2, Alpha Cardiac Actin, Alpha Smooth Muscle, Alpha-actin-2, Aortic Smooth Muscle, ASMA, Cell Growth-inhibiting Gene 46 Protein, Growth Inhibiting Gene 46) (HRP)
168642-AF-HRP Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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