CD28 (T-cell-specific surface glycoprotein CD28, Tp44) (PE)

Catalogue Number: 168684-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: CB28
Isotype: IgG1, kappa
Immunogen: Recombinant human CD28 protein. Cellular Localization: Cell surface
Application: FC

Description

Description: Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.

Additional Text

Gene ID

940

Gene Name

CD28

Uniprot ID

P10747

Purification

Protein A/G Purified

Antibody Clonality

Monoclonal