CD31 (PECAM-1, EndoCAM, PECA1, Platelet Endothelial Cell Adhesion Molecule 1, GPIIA') (Biotin)
Catalogue Number: 168685-AF-BIOTIN-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | C31.3, JC/70A |
| Isotype: | IgG1, kappa |
| Immunogen: | Human recombinant CD31 protein (C31.3) and membrane preparation of a spleen from a patient with hairy cell leukemia (JC/70A). Cellular Localization: Cell surface and cytoplasm of endothelial cells |
| Application: | FC, IF, WB, IHC |
Description
Description: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Additional Text
Gene Name
PECAM1
Gene ID
5175
Uniprot ID
P16284
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations