CD6 (T12, TP120) (MaxLight 490)
Catalogue Number: 168711-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD6 antigen|T12|T-cell differentiation antigen CD6|TP120 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | C6/372, 3F7B5 |
| Isotype: | IgG1 |
| Immunogen: | Human recombinant CD6 protein (C6/372); Human rheumatoid synovial T cell line ST-1 (3F7B5). Cellular Localization: Cell surface and cytoplasmic |
| Application: | IF, IP, WB, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular "scavenger receptor cysteine-rich" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Additional Text
Gene ID
923
Gene Name
CD6
Uniprot ID
P30203
Purification
Protein A/G Purified
Specificity
Recognizes human CD6.
Antibody Clonality
Monoclonal
168711-ML490 Datasheet
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