CD71 (Transferrin Receptor, Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR) (BSA & Azide Free) (MaxLight 490)
Catalogue Number: 168718-AF-ML490-USB
| Manufacturer: | United States Biological |
| Preservative: | BSA & Azide Free |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 66IG10 |
| Isotype: | IgG1, kappa |
| Immunogen: | Human thymocytes (T-cells). Cellular Localization: Secreted, cell surface, cell membrane, melanosome |
| Application: | FC, IF, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
Additional Text
Purification
Protein A/G Purified
Specificity
Recognizes human CD71 (Transferrin Receptor).
Antibody Clonality
Monoclonal
168718-AF-ML490 Datasheet
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