Cytokeratin 19 (k19, k1cs, Keratin 19 Keratin Type i 40kD, krt19) (BSA & Azide Free) (MaxLight 490)

Catalogue Number: 168748-AF-ML490-USB

Manufacturer:United States Biological
Preservative:BSA & Azide Free
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: BA17
Isotype: IgG1, kappa
Immunogen: Human mammary epithelial organoids. Cellular Localization: Cytoplasmic
Application: FC, IF, WB, IHC, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. This Ab reacts with the rod domain of human cytokeratin 19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Additional Text

Purification

Protein A/G Purified

Specificity

Recognizes human Cytokeratin 19. Species Crossreactivity: mouse. Others not known.

Antibody Clonality

Monoclonal