Cytokeratin 19 (k19, k1cs, Keratin 19 Keratin Type i 40kD, krt19) (APC)

Catalogue Number: 168749-APC-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Allophycocyanin (APC).
Type:Monoclonal Primary Antibody - Conjugated
Alias:40-kDa keratin intermediate filament|CK19|CK-19|cytokeratin 19|K19|K1CS|keratin 19, type I|keratin, type I cytoskeletal 19|keratin, type I, 40-kd
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: A53-B/A2.26, BA17
Isotype:
Immunogen: Human breast cancer MCF-7 cells (A53-B/A2); Human mammary epithelial organoids (BA17). Cellular Localization: Cytoplasmic
Application: IF, IHC

Description

Description: This Ab reacts with the rod domain of human cytokeratin 19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

KRT19

Gene ID

3880

Uniprot ID

P08727

Purification

Protein A/G Purified

Specificity

Recognizes the rod domain of human Cytokeratin 19 at ~40kD

Antibody Clonality

Monoclonal