MART-1 (Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA, Melan-A) (HRP)
Catalogue Number: 168825-HRP-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with horseradish peroxidase (HRP). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | antigen LB39-AA|antigen SK29-AA|epididymis secretory sperm binding protein|MART1|MART-1|melanoma antigen recognized by T-cells 1|protein Melan-A |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | DT101+ BC199 |
| Isotype: | IgG2b |
| Immunogen: | Recombinant hMART-1 protein (M2-7C10; M2-9E3). Cellular Localization: Cytoplasmic |
| Application: | IP, WB, IHC |
Description
Description: This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Additional Text
Caution
FOR RESEARCH USE ONLY
Gene ID
2315
Gene Name
MLANA
Uniprot ID
Q16655
Purification
Protein A/G Purified
Specificity
Recognizes human MART-1. Species Crossreactivity: mouse, and rat. Others-not known.
Antibody Clonality
Monoclonal
168825-HRP Datasheet
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