Myogenin (bHLHc3, cb553, Class C basic helix-loop-helix protein 3, Myf-4, MYF4, MYOG, Myogenic factor 4, Myogenin myogenin factor 4) (FITC)

Catalogue Number: 168843-FITC-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Fluorescein isothiocyanate (FITC).
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	bHLHc3\|class C basic helix-loop-helix protein 3\|MYF4\|myf-4\|myogenic factor 4\|myogenin
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	MGN185, F5D
Isotype:	IgG1, kappa
Immunogen:	Human myogenin recombinant protein (MGN185); Rat myogenin recombinant fragment containing amino acid 30-224 (F5D). Cellular Localization: Nuclear
Application:	IF, IP, WB, IHC

Overview
Datasheets

Description

Description: Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene ID

4656

Gene Name

MYOG

Uniprot ID

P15173

Purification

Protein A/G Purified

Specificity

Recognizes human Myogenin. Species Crossreactivity: mouse, rat, feline, and porcine. Others not known.

Antibody Clonality

Monoclonal

168843-FITC Datasheet

Price

£883.00

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