PAX7 (HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2) (BSA & Azide Free) (MaxLight 490)
Catalogue Number: 168852-AF-ML490-USB
| Manufacturer: | United States Biological |
| Preservative: | BSA & Azide Free |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | HUP1|paired box homeotic gene 7|paired box protein Pax-7|paired domain gene 7|PAX7 transcriptional factor|PAX7B|RMS2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | PAX7/497 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant fragment corresponding to aa 301-505 from human PAX7. Cellular Localization: Nuclear |
| Application: | FC, IF, WB |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell- derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveo- lar rhabdomyosarcoma).
Additional Text
Purification
Protein A/G Purified
Gene Name
PAX7
Specificity
Recognizes human PAX7. Species Crossreactivity: mouse, rat, chicken, zebrafish.
Gene ID
5081
Uniprot ID
P23759
Antibody Clonality
Monoclonal
168852-AF-ML490 Datasheet
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