CD43 (Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN) (HRP)

Catalogue Number: 172048-AF-HRP-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with horseradish peroxidase (HRP).
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CD43\|galactoglycoprotein\|GALGP\|GPL115\|leukocyte sialoglycoprotein\|leukosialin\|LSN\|sialophorin (gpL115, leukosialin, CD43)
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	SPM503
Isotype:	IgG1, kappa
Immunogen:	Myeloblastic KG1 cells. Cellular Localization: Cell surface
Application:	ELISA, IP, WB, IHC

Overview
Datasheets

Description

Description: It recognizes a cell surface glycoprotein of 95/115/135kD (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.

Additional Text

Gene Name

SPN

Purification

Protein A/G Purified

Specificity

Recognizes human CD43.

Gene ID

6693

Uniprot ID

P16150

Antibody Clonality

Monoclonal

172048-AF-HRP Datasheet

Price

£883.00

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Quantity
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