CD45 (B220, CD45R, GP180, Leukocyte common antigen, LCA, Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C, PTPRC, Receptor-type tyrosine-Protein phosphatase C, T200 GlycoProtein) (HRP)

Catalogue Number: 172050-AF-HRP-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with horseradish peroxidase (HRP).
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	B220\|CD45\|CD45 antigen\|CD45R\|GP180\|LCA\|L-CA\|LY5\|protein tyrosine phosphatase, receptor type, c polypeptide\|receptor-type tyrosine-protein phosphatase C\|T200\|T200 glycoprotein\|T200 leukocyte common antigen
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	SPM570
Isotype:	IgG1, kappa
Immunogen:	Isolated neoplastic cells from T cell lymphoma. Cellular Localization: Cell surface and cytoplasmic
Application:	ELISA, IP, WB, IHC

Overview
Datasheets

Description

Description: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

Additional Text

Gene Name

PTPRC

Gene ID

5788

Uniprot ID

P08575

Purification

Protein A/G Purified

Specificity

Recognizes human CD45.

Antibody Clonality

Monoclonal

172050-AF-HRP Datasheet

Price

£883.00

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