CD45RA (B220, CD45R, GP180, Leukocyte common antigen, LCA, Loc, Ly-5, Lyt-4, Protein tyrosine phosphatase receptor type C, PTPRC, Receptor-type tyrosine-Protein phosphatase C, T200 GlycoProtein) (HRP)

Catalogue Number: 172052-AF-HRP-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with horseradish peroxidase (HRP).
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	B220\|CD45\|CD45 antigen\|CD45R\|GP180\|LCA\|L-CA\|LY5\|protein tyrosine phosphatase, receptor type, c polypeptide\|receptor-type tyrosine-protein phosphatase C\|T200\|T200 glycoprotein\|T200 leukocyte common antigen
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	SPM568
Isotype:	IgG2a, kappa
Immunogen:	Stimulated human leukocytes. Cellular Localization: Cell surface
Application:	ELISA, IP, WB, IHC

Overview
Datasheets

Description

Description: Recognizes a protein of 205kD-220kD, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).

Additional Text

Gene Name

PTPRC

Gene ID

5788

Uniprot ID

P08575

Purification

Protein A/G Purified

Specificity

Recognizes human CD45RA.

Antibody Clonality

Monoclonal

172052-AF-HRP Datasheet

Price

£883.00

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