CD56 (NCAM, Leu-19, NKH1, MSK39, NCAM1, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule) (Biotin)
Catalogue Number: 172057-AF-BIOTIN-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Biotin. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | SPM128 |
| Isotype: | IgG1, kappa |
| Immunogen: | Membrane preparation of a small cell lung carcinoma. Cellular Localization: Cell surface |
| Application: | ELISA, IF, IP, WB, IHC |
Description
Description: This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kD isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Additional Text
Gene Name
NCAM1
Gene ID
4684
Uniprot ID
P13591
Purification
Protein A/G Purified
Specificity
Recognizes CD56. Species Crossreactivity: Human, Rat and Zebrafish.
Antibody Clonality
Monoclonal
SUPPORT
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PRODUCT
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DELIVERY
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