Catalogue Number: 172067-AF-ML650-USB
| Manufacturer: | United States Biological |
| Preservative: | BSA & Azide Free |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | betagranin (N-terminal fragment of chromogranin A)|catestatin|CGA|chromofungin|chromogranin-A|parathyroid secretory protein 1|pituitary secretory protein I|SP-I |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | SPM553 |
| Isotype: | IgG1, kappa |
| Immunogen: | Recombinant protein corresponding to human chromogranin A protein. Cellular Localization: Finely granular cytoplasmic |
| Application: | FC, IF, IHC, FLISA |
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
1113
CHGA
P10645
Protein A/G Purified
Recognizes human chromogranin A.
Monoclonal