IgA Secretory Component (ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD) (BSA & Azide Free) (MaxLight 490)

Catalogue Number: 172110-AF-ML490-USB

Manufacturer:United States Biological
Preservative:BSA & Azide Free
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Secondary Antibody - Conjugated
Alias:extracellular matrix protein 1|secretory component p85|testicular tissue protein Li 61|URBWD
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: SPM217
Isotype: IgG1, kappa
Immunogen: Secretory Component protein isolated from human colostrum. Cellular Localization: Cell surface and cytoplasmic
Application: IF, IP, WB, IHC, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.

Additional Text

Gene Name

ECM1

Purification

Protein A/G Purified

Specificity

Recognizes IgA Secretory Component. Species Crossreactivity: Human and Rat.

Gene ID

1893

Uniprot ID

Q16610

Antibody Clonality

Monoclonal