IgM (AGM1, IGHM, Constant Region of Heavy Chain of IgM, Ig Mu Chain C Region, Immunoglobulin Mu Heavy Chain) (BSA & Azide Free) (MaxLight 490)

Catalogue Number: 172112-AF-ML490-USB

Manufacturer:United States Biological
Preservative:BSA & Azide Free
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Secondary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: SPM557
Isotype: IgG1, kappa
Immunogen: Recombinant heavy chain of human IgM. Cellular Localization: Cytoplasm, Cell Surface and Secreted
Application: IF, IHC, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Recognizes a protein of 75kD, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Additional Text

Purification

Protein A/G Purified

Specificity

Recognizes human IgM.

Uniprot ID

P01871

Antibody Clonality

Monoclonal