Neurofilament (NEFH, Neurofilament H, Neurofilament Heavy Polypeptide 200kD, Neurofilament Triplet H Protein, NF-H, NF200, NF-H) (BSA & Azide Free) (MaxLight 490)

Catalogue Number: 172132-AF-ML490-USB

Manufacturer:	United States Biological
Preservative:	BSA & Azide Free
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	200 kDa neurofilament protein\|CMT2CC\|neurofilament heavy polypeptide\|neurofilament triplet H protein\|neurofilament, heavy polypeptide 200kDa\|NFH\|NF-H
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	SPM563
Isotype:	IgG1, kappa
Immunogen:	Human recombinant neurofilament protein. Cellular Localization: Cytoplasm, cytoskeleton, cell projection and axon
Application:	FC, WB, IHC, FLISA

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. This MAb reacts with a 200kD protein, identified as heavy sub-unit of neurofilaments (NF-H). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kD (NF-L), 160kD (NF-M) and 200kD (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.

Additional Text

Gene Name

NEFH

Gene ID

4744

Purification

Protein A/G Purified

Specificity

Recognizes Neurofilament. Species Crossreactivity: Human, Mouse, Rat, Porcine and Chicken.

Uniprot ID

P12036

Antibody Clonality

Monoclonal

172132-AF-ML490 Datasheet

Price

£883.00

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