ICG-Sulfo-EG8-OSu

Catalogue Number: 184-AAT

Manufacturer:AAT Bioquest
Shelf Life:12 months
Type:Fluorescent Reagents
Shipping Condition:RT
Unit(s): 1 mg

Description

Description: Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography. It has a peak spectral absorption close to 800 nm. These infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography. Conventional activated ICG dye, ICG-Sulfo-OSu, has been used for preparing ICG-antibody conjugates utilized in in vivo imaging research as antibody conjugates. However, the ICG hydrophobicity often causes some unspecific bindings. The PEG-modified ICG dyes are used to increase the hydrophilicity of the ICG dyes. The PEGylated ICGs shows better water solubility and significantly reducing unspecific binding.

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Storage Note

Freeze (< -15 °C); Minimize light exposure;|12 months