Catalogue Number: 184-AAT
Manufacturer: | AAT Bioquest |
Shelf Life: | 12 months |
Type: | Fluorescent Reagents |
Shipping Condition: | RT |
Unit(s): | 1 mg |
Description: Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography. It has a peak spectral absorption close to 800 nm. These infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography. Conventional activated ICG dye, ICG-Sulfo-OSu, has been used for preparing ICG-antibody conjugates utilized in in vivo imaging research as antibody conjugates. However, the ICG hydrophobicity often causes some unspecific bindings. The PEG-modified ICG dyes are used to increase the hydrophilicity of the ICG dyes. The PEGylated ICGs shows better water solubility and significantly reducing unspecific binding.
Freeze (< -15 °C); Minimize light exposure;|12 months