Anti-Human COX-1 (C24) Rabbit IgG Affinity Purify 18511

Catalogue Number: 18511-IBL

Manufacturer:	IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:	Polyclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	100 ug, 10 ug
Host name:	Rabbit
Clone:
Isotype:	IgG
Immunogen:	Synthetic peptide of the C terminal site of Human COX-1 (ADPGAPTPVNPC)
Application:	WB

Overview
Datasheets

Description

Description: COX-1 and COX-2 (Cyclooxygenase 1,2) are also called prostaglandin endoperoxide H synthase, and are important enzymes as catalysts for the reaction in prostaglandin H2 (PGH2) synthesis from the arachidonic acid. COX-1 and COX-2 have the homology of about 60% at the amino acid level. COX-1 is expressed constitutively in many organs such as kidney, stomach, vascular smooth muscle or platelets widely and it is thought to play a so-called housekeeping role. On the other hand, COX-2 cannot be usually detected from organs, however, it is high-level expressed by macrophage and other cells in response to the stimulation such as various cytokines, hormones, the tumor cause medicines, inflammation mediators, or mitogens, therefore, it is thought that COX-2 produces prostaglandin in relation to the inflammation condition.

Additional Text

Purification

Affinity Purified

Antibody Clonality

Polyclonal

18511 Datasheet

Price

£333.00

-

Quantity
Unit Size

Find out about delivery