Anti-Human IκB-α (I037) Rabbit IgG Affinity Purify

Catalogue Number: 18669-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Physical state:Lyophilized product from 1% BSA in PBS containing 0.05% NaN3
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name:
Clone:
Isotype:
Immunogen: Synthetic peptide in portion of N-terminus of Human IκB-α protein

Description

Description: In signal transduction system, IκB acts as inhibitor to forms complex with NF-κB in cytoplasm and subsequently to inactivate NF-κB. NF-κB is transcription factor distributed in various cells. NF-κB is considered to control various gene expression by degradation of IκB and subsequent translocation of degradation products to nuclear in accordance with various stimulation.

Additional Text

Specificity

Confirmed by Human IκB-α The sequence of synthetic peptide used for antigen has homology of 100% to that of mouse. However, sample of mouse by this antibody is not tested.