Catalogue Number: 18669-IBL
|Manufacturer:||IBL - (Immuno-Biologicals Laboratories Co Ltd)|
|Physical state:||Lyophilized product from 1% BSA in PBS containing 0.05% NaN3|
|Type:||Polyclonal Primary Antibody - Unconjugated|
|Shipping Condition:||Blue Ice|
|Immunogen:||Synthetic peptide in portion of N-terminus of Human IκB-α protein|
Description: In signal transduction system, IκB acts as inhibitor to forms complex with NF-κB in cytoplasm and subsequently to inactivate NF-κB. NF-κB is transcription factor distributed in various cells. NF-κB is considered to control various gene expression by degradation of IκB and subsequent translocation of degradation products to nuclear in accordance with various stimulation.
Confirmed by Human IκB-α The sequence of synthetic peptide used for antigen has homology of 100% to that of mouse. However, sample of mouse by this antibody is not tested.