Catalogue Number: 18751-IBL
Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
Type: | Polyclonal Primary Antibody - Unconjugated |
Shipping Condition: | Blue Ice |
Storage Condition: | 2-8°C |
Unit(s): | 100 ug, 10 ug |
Host name: | Rabbit |
Clone: | |
Isotype: | IgG |
Immunogen: | Maltose Binding Protein (MBP) - Syndecan-4 recombinant protein |
Application: | WB, IHC |
Description: Syndecan, a cell surface proteoglycan, is an integral membrane protein acting as a receptor for the extracellular matrix. The syndecan family of four transmembrane heparan sulfate proteoglycans binds a variety of soluble and insoluble extracellular effectors. Syndecan extracellular domains (ectodomains) can be shed intact by proteolytic cleavage of their core proteins, yielding soluble proteoglycans that retain the binding properties of their cell surface precursors. The syndecan-4 acts in conjunction with the α5β1 integrin to promote the formation of actin stress fibers and focal adhesions in fibronectin-adherent cells.
Affinity Purified
Polyclonal