Anti-RET Finger Protein (RFP) Rabbit IgG Affinity Purify 18791
Catalogue Number: 18791-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 10 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide for C-terminal portion of RFP (IDGFSGHVGNHGHSMETSP) |
| Application: | ICC, IP, WB, IHC |
Description
Description: RET finger protein (RFP) belongs to the large B-box RING finger protein family and is known to become oncogenic by fusion with RET tyrosine kinase. Although RFP is reported to be a nuclear protein that is present in the nuclear matrix, its function is largely unknown. RFP interacts with Enhancer of Polycomb (EPC) and strongly represses the gene transcription. Yeast two-hybrid assays revealed that the coiled-coil domain of RFP was associated with the EPcA domain and the carboxyl-terminal region of EPC. RFP may be involved in the epigenetic gene silencing mechanism cooperating with Polycomb group protein.
Additional Text
Purification
Affinity Purified
Antibody Clonality
Polyclonal
18791 Datasheet
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