Anti-Human GLUT-3 Rabbit IgG Affinity Purify 18903

Catalogue Number: 18903-IBL

Manufacturer:IBL - (Immuno-Biologicals Laboratories Co Ltd)
Type:Polyclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug, 10 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide of the C terminal part of human GLUT-3 (SGKDGVMEMNSIEPAKETT)
Application: WB, IHC

Description

Description: Mammalian cells transport glucose through a family of membrane proteins known as glucose transporters (GLUTs or SLC2A family). Mammalian tissues are known to express different glucose transporter isoforms (exisiting at least GLUTs 1-13) in different tissues. The molecular weight are 40-60 kDa, respectively. GLUT-1 has a high affinity with glucose (Km 1-5 mM) and mediates glucose transport into red cells, and throughout the blood brain barrier. It is ubiquitously expressed and transport glucose in most cells, such as red cells, embryo tissues, brain, kidney or tumor cells. GLUT-3 has a high affinity with glucose (Km 1 -5 mM) and is the main transporter in brain (neurons). GLUT-5 transports fructose in intestine and testis. Especially, our GLUT-5 antibody detects microglia selectively in immnostaining, and doesn't react with monocytes and monocyte-derived macrophages. Immunostaining by this antibody excels in the form observation compared with staining by other antibodies reported as microglia markers, and it makes it easy to distinguish between a static type and an active type in the form observation.

Additional Text

Purification

Affinity Purified

Antibody Clonality

Polyclonal