Anti-Synaptotagmin IV Rabbit IgG Affinity Purify
Catalogue Number: 18977-IBL
| Manufacturer: | IBL - (Immuno-Biologicals Laboratories Co Ltd) |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 10 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant Synaptotagmin IV C2A domain |
| Application: | ICC, IP, WB |
Description
Description: Synaptotagmin family proteins consist of a single N-terminal transmembrane domain and C-terminal tandem C2 domains (C2A and C2B), which have the ability to bind Ca2+ and phospholipid, and 15 synaptotagmin isoforms have been reported in the mouse and humans to date. The best-characterized isoform, synaptotagmin I, is essential for synaptic vesicle exocytosis and endocytosis. It has been reported that i) synaptotagmin IV expression is regulated by neural activity and that it is thought to be involved in synaptic plasticity, ii) that synaptotagmin IV is present on dense-core vesicles in NGF-differentiated PC12 cells and may control their exocytosis, and iii) that synaptotagmin IV regulates glutamate release by astrocytes.
Additional Text
Purification
Affinity Purified
Antibody Clonality
Polyclonal
18977 Datasheet
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