Catalogue Number: 18981-IBL
|Manufacturer:||IBL - (Immuno-Biologicals Laboratories Co Ltd)|
|Physical state:||Lyophilized product from 1% BSA in PBS containing 0.05% NaN3|
|Type:||Polyclonal Primary Antibody - Unconjugated|
|Shipping Condition:||Blue Ice|
|Unit(s):||100 ug, 10 ug|
|Immunogen:||Synthetic peptide of the C terminal of Human dbpA (TENPAPPTQQSSAE)|
Description: DbpA (DNA Binding protein A) belongs to the Y-box binding protein family that contain a DNA binding domain, called the cold shock domain, of about 80-amino-acid residues. DbpA was identified as the protein binding to the epidermal growth factor receptor enhancer or c-erbB-2 ptomoter. These Y-box binding proteins are reported to have maultiple function, such as the regulations of transvription and translation. It was reported that dbpA was a candidate molecule to accelerate the process of the inflammation-induced hepatocarcinogenesis, the association with the advanced stages of hepatocellular carcinoma and its nuclear localization as a marker of poor prognosis.