Direct Salivary 17-OH Progesterone EIA (96 wells), "IVD"
Catalogue Number: 20-17OHU-E01-SLV-ALP
| Manufacturer: | Alpco Diagnostics |
| Type: | Human ELISA Kit |
| Alias: | Progesterone |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 96 Wells |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: | |
| Range: | 0.005 - 5 ng/mL |
| Sensitivity: | 0.003 ng/mL |
| Sample type: | Saliva |
| Sample size: | 25 µL |
| Application: | IA, EIA |
Description
Description: The steroid 17-α-Hydroxyprogesterone (17-α-OHP) is produced by both the adrenal cortex and gonads. Even though 17-α-OHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17-α-OHP, measurement of 17-α-OHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of Congenital Adrenal Hyperplasia (CAH), 17-α-OHP is secreted in abundant excess. It is moderately elevated in the 11-β-hydroxylase deficiency as well. Measurement of 17-α-OHP is therefore valuable in the initial diagnosis of CAH.
Additional Text
Short Description
The 17-alpha Hydroxy Progesterone ELISA (Saliva) is intended for the quantitative determination of 17 a-Hydroxyprogesterone (17 OHP) in human saliva.
Storage Note
store at 2-8C
20-17OHU-E01-SLV Protocol
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