Annexin V-mFluor™ Violet 450 conjugate
Catalogue Number: 20080-AAT
| Manufacturer: | AAT Bioquest |
| Shelf Life: | 6 months |
| Type: | Protein - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
Description
Description: Annexins are a family of proteins that bind to phospholipid membranes in the presence of calcium. Annexin V is a valuable tool for studying cell apoptosis. It is used as a probe to detect cells which have expressed phosphatidylserine on the cell surface, a feature found in apoptosis as well as other forms of cell death. There are a variety of parameters that can be used for monitoring cell viability. Annexin V-dye conjugates are widely used to monitor cell apoptosis through measuring the translocation of phosphatidylserine (PS). In apoptosis, PS is transferred to the outer leaflet of the plasma membrane. The appearance of phosphatidylserine on the cell surface is a universal indicator of the initial/intermediate stages of cell apoptosis and can be detected before morphological changes can be observed. This fluorescent Annexin V conjugate has spectral properties similar to Pacific Blue® (Pacific Blue® is the trademark of Invitrogen) with Ex/Em = ~400/450 nm. The blue fluorescent stain is well excited with the Violet Laser at 405 nm, and emits intense blue fluorescence at ~450 nm.
Additional Text
Storage Note
Freeze (< -15 °C); Minimize light exposure;|6 months
20080 Protocol
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