Vascular Endothelial Growth Factor-A (VEGF-A, VPF)
Catalogue Number: 207434-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a lyophilized powder. Reconstitute with sterile dH2O to 0.1-1mg/ml. |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 200 ug |
| Host name: | Mouse |
| Clone: | 3(6D3) |
| Isotype: | IgG1 |
| Immunogen: | Recombinant protein corresponding to human VEGF 165. |
| Application: | ELISA, WB, NT |
Description
Description: Human vascular endothelial erowth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF-A is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Recognizes human Vascular Endothelial Growth Factor-A.
Purification
Protein G purified
Antibody Clonality
Monoclonal
207434 Datasheet
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