HSPA1A (FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1, HSPA1B) (ATTO 488)

Catalogue Number: 207714-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide, 50% glycerol. Labeled with ATTO 488.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ug
Host name: Mouse
Clone: 5A5
Isotype: IgG1
Immunogen: Recombinant protein corresponding to human HSPA1A.
Application: ICC, IF, IP, WB, IHC

Description

Description: This intronless gene encodes a 70kD heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Additional Text

Caution

FOR RESEARCH USE ONLY

Accession Number

NP_005336.3

Specificity

Recognizes human HSPA1A. Detects several members of the heat shock protein 70kD gene family including Hsp70, Hsc70, Grp78 and following heat shock, Hsp72. Species Crossreactivity: amphibia, chicken, fish, drosophila, mouse, rat, yeast.

Purification

Protein G purified

Antibody Clonality

Monoclonal