SARS-CoV-2 Spike S1 Mutant Sampler Set
Catalogue Number: 21-1013-ABO
21-1013 Image
21-1013 Image
21-1013 Image
Figure-1: Recombinant SARS-CoV-2 Spike S1 wild type (WT), N439K, D614G, K417N/E484K/N501Y and S13l/W152C/L452R mutant proteins were run on a 4-20% SDS-PAGE gel followed by Coomassie blue staining.
21-1013 Image
Figure-2: Comparative binding of Spike S1 variants to sACE2: Wells of a 96-well microtiter plate were coated with 100 ng in duplicates each of S1-WT (Cat# 21-1008), S1-N439K (Cat# 21-1012), S1-D614G (Cat# 21-1009), S1-South Africa (Cat# 21-1017), and S1-Southern California (Cat# 21-1018). Binding to sACE2 was determined by adding different concentrations of biotinylated-sACE2 (Cat# 21-1006).
| Manufacturer: | Abeomics |
| Type: | Other Recombinant Protein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 x 5 ug |
| Application: | ELISA |
Description
Description: This SARS-CoV-2 Spike S1 Mutant Sampler Set contains: wild type Spike S1 protein (Cat. No. 21-1008), D614G mutant (Cat. No. 21-1009), N439K mutant (Cat. No. 21-1012), K417N/E484K/N501Y (South African) mutant (Cat. No. 21-1017), and S13l/W152C/L452R (Southern California) mutant (Cat. No. 21-1018) recombinant proteins expressed in CHO-K1. The spike protein S1 subunit of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S1 mediates this interaction. The S protein plays key parts in the induction of neutralizing antibodies and T-cell responses, as well as protective immunity.
21-1013 Datasheet
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