CFLAR (CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1)

Catalogue Number: 214300-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, 0.05% sodium azide, 0.5% protein stabilizer.
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: 14i115
Isotype: IgG
Immunogen: Recombinant protein corresponding to aa100-251 from human CFLAR expressed in E. coli.
Application: ELISA, WB, IHC

Description

Description: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.

Additional Text

Specificity

Recognizes human CFLAR.

Purification

Purified

Antibody Clonality

Monoclonal