SLC2A4 (GLUT4, Glucose Transporter Type 4)

Catalogue Number: 214422-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in 0.03% sodium azide.
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 14i237
Isotype: IgG
Immunogen: Recombinant protein corresponding to aa224-353 from human SLC2A4 expressed in E. coli.
Application: ELISA, FC, ICC, WB, IHC

Description

Description: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

Additional Text

Specificity

Recognizes SLC2A4. Species Crossreactivity: human, mouse.

Antibody Clonality

Monoclonal