Catalogue Number: 214472-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | AGC1|AGCAN|aggrecan core protein|cartilage-specific proteoglycan core protein|chondroitin sulfate proteoglycan core protein 1|CSPG1|CSPGCP|large aggregating proteoglycan|MSK16|SEDK|SSOAOD |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 7D4 |
| Isotype: | IgG1 |
| Immunogen: | Purified human articular cartilage aggrecan. |
| Application: | IP, WB, IHC, FLISA |
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. Aggrecan, is a proteoglycan and member of the aggrecan/versican proteoglycan family, which forms a major component of the extracellular matrix (ECM) of both cartilage and the central nervous system (CNS). Studies using a panel of core protein-directed antibodies against human aggrecan, revealed the distribution of different aggrecan isoforms within the CNS, and sub-divided the isoforms into clusters 1-5 accordingly. These studies also showed a difference in the relative abundance of these isoforms when comparing brain and cartilage tissues (Virgintino et al. 2009).
176
ACAN
Recognizes human Aggrecan. Species Crossreactivity: bovine. Does not cross-react with chicken, fish or rat.
Protein G purified
P16112
Monoclonal