CD152 (CTLA-4, Cytotoxic T-lymphocyte Protein 4) (FITC)

Catalogue Number: 214583-FITC-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. Labeled with fluorescein isothiocyanate (FITC).
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	Cd152\|CD152 antigen\|Ctla-4\|cytotoxic T-lymphocyte protein 4\|cytotoxic T-lymphocyte-associated antigen 4\|Ly-56
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Hamster
Clone:	1B8
Isotype:	IgG
Immunogen:	Extracellular portion of mouse CD152 fused to a mouse IgG2a.
Application:	FC, IF, IP, WB, FLISA

Overview
Datasheets

Description

Description: CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.

Additional Text

Gene ID

12477

Gene Name

CTLA4

Specificity

Recognizes mouse CD152

Purification

Protein G purified

Uniprot ID

P09793

Antibody Clonality

Monoclonal

214583-FITC Datasheet

Price

£832.00

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