CD16 (FcRIII) (MaxLight 650)
Catalogue Number: 214585-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | KD1 |
| Isotype: | IgG2a |
| Immunogen: | A polyclonal population of NK cells |
| Application: | NT |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages (Moretta et al. 1990), whereas CD16B is primarily expressed by granulocytes (Bonecchi et al. 1999). Recognizes both forms of CD16 and will therefore recognize all cell types expressing CD16.
Additional Text
Specificity
Recognizes human CD16. Species Crossreactivity: bovine, sheep. Reacts weakly with equine and porcine. Does not react with canine and rat.
Purification
Protein G purified
Uniprot ID
P79107
Antibody Clonality
Monoclonal
214585-ML650 Datasheet
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