CD4 (MaxLight 490)
Catalogue Number: 214685-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD4 antigen (p55)|T-cell surface antigen T4/Leu-3|T-cell surface glycoprotein CD4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | YKIX302.9 |
| Isotype: | IgG2a |
| Immunogen: | Canine Concanavilin A activated T-cell blasts |
| Application: | FC, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Clustered at the first Canine Leukocyte Antigen Workshop (CLAW) [Cobbold et al. 1992]. Rat anti canine CD4 has been demonstrated to partially deplete circulating T lymphocytes when administered in vivo, but alone was not sufficient to prolong allograft survival in a canine transplant model (Watson et al. 1993). Uniquely amongst mammals, canine CD4 is expressed by neutrophils as well as by lymphocytes subsets Moore et al. 1992. Rat anti Canine CD4 forms part of a panel of anti canine monoclonal antibodies used extensively in the evaluation of leukemic status in dogs (Villiers 2002).
Additional Text
Gene Name
CD4
Specificity
Recognizes canine CD4.
Purification
Protein G purified
Uniprot ID
P33705
Gene ID
403931
Antibody Clonality
Monoclonal
214685-ML490 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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