GFAPC (Glial Fibrillary Acidic Protein) (APC)
Catalogue Number: 214855-APC-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2E1 |
| Isotype: | IgG2b |
| Immunogen: | Bovine spinal cord homogenate. |
| Application: | RIA |
Description
Description: Glial fibrillary acidic protein, or GFAP, a class III intermediate filament. During development of the central nervous system, GFAP distinguishes astrocytes from other glial cells. It is involved in various cellular functions, such as cell structure and movement, cell communication and the functioning of the blood-brain barrier. It also plays a role in mitosis by adjusting the filament network present in the cell. Defects in GFAP are a cause of Alexander disease, a rare disorder of the central nervous system affecting mostly males. It is a progressive leukoencephalopathy resulting in mental and physical retardation, dementia, seizures and early death.
Additional Text
Gene Name
GFAP
Gene ID
2670
Specificity
Recognizes bovine GFAP. Species Crossreactivity: Human, mouse, rat, sheep, canine, porcine, rabbit, guinea pig, chicken
Purification
Protein G purified
Uniprot ID
P14136
Antibody Clonality
Monoclonal
214855-APC Datasheet
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