HbA1c (Haemoglobin beta Chain) (MaxLight 550)
Catalogue Number: 214867-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Human |
| Clone: | AbD15783-IgG |
| Isotype: | IgG1 |
| Immunogen: | Glycated peptide corresponding to N-terminal 9aa of haemoglobin beta chain, coupled to the carrier proteins BSA and TRF. |
| Application: | FLISA |
Description
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. Specifically recognizes HbA1c, hemoglobin glycated at the N-terminal valine of the hemoglobin b chain. It does not bind to non-glycated hemoglobin. Besides binding to the normal glycated hemoglobin, c also recognizes the glycated hemoglobin variants HbC, HbE, HbD and to a lesser degree HbS. Elevated HbF is not detected due to the absence of the hemoglobin b chain. The measurement of HbA1c levels is used to identify the average plasma glucose concentration. In diabetes mellitus, higher levels of HbA1c have been associated with cardiovascular disease and other diseases. Levels of more than 6.5% HbA1c (48mmol/mol) are used as a criterion to diagnose diabetes.
Additional Text
Specificity
Recognizes human HbA1c.
Purification
Protein A purified
Antibody Clonality
Monoclonal
214867-ML550 Datasheet
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