Surfactant Protein D (SP-D, SFTPD) (PE)

Catalogue Number: 215146-PE-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	lung surfactant protein D\|PSP-D\|pulmonary surfactant-associated protein D\|SP-D\|surfactant, pulmonary-associated protein D
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	1.7
Isotype:	IgG1
Immunogen:	Purified porcine surfactant protein D
Application:	IF, WB, IHC

Overview
Datasheets

Description

Description: Surfactant protein D (pSP-D), is a 138kD member of the collectin family of proteins. Surfactant protein D is thought to play a significant role in the innate immune response against microorganisms within the lungs and at other mucosal surfaces. SP-D is a multifunctional protein which binds selectively to saccharides and lipids on microbial surfaces promoting antimicrobial responses and regulating surfactant lipid homeostasis. SP-D expression is induced in lung surfactant in response to aerogenous bacterial infection, and upon binding to bacteria, promotes phagocytosis and antigen presentation by dendritic cells. Recent studies suggest that pSP-D could serve as a serum biomarker specific for bronchopneumonia in pigs.

Additional Text

Gene Name

SFTPD

Specificity

Recognizes porcine surfactant protein D (pSP-D).

Purification

Protein G purified

Uniprot ID

Q9N1X4

Gene ID

397198

Antibody Clonality

Monoclonal

215146-PE Datasheet

Price

£909.00

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