CD3

Catalogue Number: 216287-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rat
Clone: 14L191
Isotype: IgG2b
Immunogen: Mouse CD3 positive cells.
Application: FC, IP, IHC

Description

Description: CD3 is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3e, z, y and d chains. It forms a TCR complex by associating with TCR a/v or y/x chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. Recognizes e/y of CD3 complex.

Additional Text

Purification

Protein G purified

Antibody Clonality

Monoclonal