CD40 Ligand (CD154, CD40-L)

Catalogue Number: 216307-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Hamster
Clone: 14L211
Isotype: IgG2
Immunogen: Mouse Th1 cells.
Application: FC, IHC

Description

Description: Human CD154 (CD40 Ligand) is a member of the tumor necrosis factor (TNF) family and is expressed on the surface of activated T cells. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. CD154 has been shown to be hyperexpressed by B and T cells in SLE patients.

Additional Text

Purification

Protein A/G Purified

Antibody Clonality

Monoclonal