LPAM-1 (Integrin alpha4-beta7)
Catalogue Number: 216794-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | 14L698 |
| Isotype: | IgG2 |
| Immunogen: | Cell lysates of mouse lymphocytes. |
| Application: | FC, IP, IHC |
Description
Description: Integrin a4b7 is composed of a 150kD (a4 or CD49d) and a 130kD (b7) heterodimer, also known as CD49d/b7, or LPAM-1. It belongs to Ig superfamily found on majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin a4b7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and helps direct the migration of blood lymphocytes to the intestine and associated lymphoid tissues.
Additional Text
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
216794 Datasheet
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