Rhodopsin, CT (RHO, Opsin-2, OPN2) (MaxLight 650)

Catalogue Number: 217747-ML650-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	CSNBAD1\|OPN2\|opsin 2, rod pigment\|opsin-2\|rhodopsin\|RP4
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	Rho 1D4
Isotype:	IgG1
Immunogen:	Bovine rhodopsin. Epitope: C-terminus, last 9 amino acids
Application:	ICC, IP, WB, IHC

Overview
Datasheets

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal. Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form, which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.

Additional Text

Gene ID

6010

Uniprot ID

P08100

Gene Name

RHO

Specificity

Recognizes Bovine rhodopsin. Species Crossreactivity: vertebrates.

Purification

Protein A purified

Accession Number

NM_000539.2

Antibody Clonality

Monoclonal

217747-ML650 Datasheet

Price

£1,090.00

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