Tumor Necrosis Factor (TNF, TNF-alpha, TNFA, TNF-a, Cachectin, DIF, Tumor Necrosis Factor Ligand Superfamily Member 2, TNFSF2) (MaxLight 650)

Catalogue Number: 217855-ML650-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Alias:APC1 protein|cachectin|DIF|TNF, macrophage-derived|TNF, monocyte-derived|TNFA|TNF-a|TNF-alpha|TNFSF2|TNLG1F|tumor necrosis factor|tumor necrosis factor ligand 1F|tumor necrosis factor ligand superfamily member 2|tumor necrosis factor-alpha
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 195
Isotype: IgG3
Immunogen: Recombinant protein corresponding to human tumor necrosis factor-alpha expressed in E. coli.
Application: ICC, WB, IHC, NT

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.

Additional Text

Gene Name

TNF

Gene ID

7124

Uniprot ID

P01375

Specificity

Recognizes human natural and recombinant TNF-alpha. lt does not react with human TNF-beta (lymphotoxin). lt does not react with TNF-alpha from mouse, rat, canine, porcine, rhesus-monkey or baboon.

Purification

Purified

Antibody Clonality

Monoclonal