IGF-1 (mouse, rat) ELISA, 96 wells, "RUO"

Catalogue Number: 22-IG1MS-E01-ALP

Manufacturer:Alpco Diagnostics
Type:Mouse ELISA Kit
Shipping Condition:RT
Unit(s): 96 Wells
Range: 0.5 - 18 ng/mL
Sensitivity: 0.029 ng/mL
Sample type: Plasma, Serum
Sample size: 5 µL
Application: ELISA, IA

Description

Description: Beside different cell culture models and studies with human patients, mice and rats are suitable model organisms for basic research and pre-clinical studies. Thus, this test system was developed as a tool for IGF-I measurements in mice and rat for usage in research and pre-clinical studies. Even if the comparability of mice and humans is limited some background information on the human IGF-I system follows: Insulin-like growth factors (IGF) I and II play a pivotal role in regulating the proliferation, differentiation and specific functions of many cell types. IGF-I is identical with Somatomedin C (Sm-C) and has a molecular weight of 7649 daltons. Its major regulators are growth hormone (GH) and nutrition, although its production in specific tissues is affected by a multitude of tropic hormones and other peptide growth factors. In contrast to many other peptide hormones, IGFs are avidly bound to specific binding proteins (IGFBP).

Additional Text

Regulatory Statuses

Research Use Only. Not for Use in Diagnostic Procedures.

Short Description

The Mouse / Rat IGF-1 ELISA is for the quantitative determination of IGF-1 in rat and mouse serum and plasma. Dynamic range 0.5-18 ng/mL Sensitivity 0.029 ng/mL Sample size 5 uL