Catalogue Number: 227214-FITC-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with fluorescein isothiocyanate (FITC). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 15B488 |
| Isotype: | IgG1 |
| Immunogen: | Cardiac Troponin I. |
| Application: | ELISA, LF |
Description: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.
Recognizes Cardiac Troponin I.
Affinity Purified
Monoclonal