Troponin I (FITC)

Catalogue Number: 227214-FITC-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with fluorescein isothiocyanate (FITC).
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 15B488
Isotype: IgG1
Immunogen: Cardiac Troponin I.
Application: ELISA, LF

Description

Description: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

Additional Text

Specificity

Recognizes Cardiac Troponin I.

Purification

Affinity Purified

Antibody Clonality

Monoclonal